#ANALYSE SPECTRALE RMN MANUAL#
#ANALYSE SPECTRALE RMN SOFTWARE#

#ANALYSE SPECTRALE RMN SOFTWARE#

Fortunately, over the past few years, several software tools have been developed that largely automate the spectral deconvolution or spectral annotation process.

#ANALYSE SPECTRALE RMN MANUAL#

In many cases, manual spectral annotation and analysis can take one or more hours per spectrum. However, a continuing bottleneck in NMR-based metabolomics has been the time required to manually analyze and annotate the collected NMR spectra. All this instrumental automation allows NMR data to be collected at a rate of >100 samples/day. Likewise, more and more instruments, especially for NMR-based metabolomics applications, are equipped with automated sample changers. Most modern NMR spectrometers are now equipped with auto-tune/auto-match probes along with automated locking and shimming systems.

Química C/ Martí i Franquès, MONTSERRATĮdifici Clúster (PCB) C/ Baldiri Reixac, LOPEZ-IBARRAĮdifici Clúster (PCB) C/ Baldiri Reixac, FERNANDEZĮdifici Clúster (PCB) C/ Baldiri Reixac, MIELGOįac.Nuclear magnetic resonance (NMR) spectroscopy is becoming increasingly automated. Química C/ Martí i Franquès, TAHULLĮdifici Clúster (PCB) C/ Baldiri Reixac, ORTIZįac.

Consulting and training for the optimization of the use of existing NMR instrumentation at private centers.įac.

Application of NMR in the analysis of food products (oils, dairy, juices, additives, etc.).

Determination of the degree of deuteration.

Quantitative analysis through the use of internal patterns.

Study of metabolites resulting from the application of an active ingredient (whether directly or through a prior HPLC system treatment).

Identification analysis for compliance with REACH standard.

PGLA polymer analysis (in accordance with ASTM standards).

Poloxamer analysis (according to EP, USP procedure).

Heparin analysis (in compliance with FDA-USP and European and Japanese Pharmacopoeia standards).

NMR spectral assignment for the identification of structures.

Identification of compounds, spectral assignment, reports and evaluations.

Work conducted in accordance with standardized procedures (SOP) for the analysis of APIs (USP, European Pharmacopoeia and ASTM standards).

Determination of interactions between proteins and low-molecular weight compounds.

Process monitoring, kinetic monitoring variable temperature experiments.

Control of synthesis processes and/or purification of organic compounds Determination of impurities and minority components quantitative analyses.

Implementation of new sequences and methods methodological development and application.

Combined use of 1H, 13C and 15N for the study of complex molecules such as proteins through 2 and 3D inverse detection experiments.

Analysis of complex structures (natural products, compounds of biological interest) Multi-dimensional experiments for structural determination in proteins.

Combined experiments such as HMQC-TOCSY and other heteronuclear experiments.One- and two-dimensional experiments (COSY, DQF, COSY, TOCSY, HSQC, HMBC, NOESY).Structural determination of organic and inorganic compounds (small-medium molecular weight).NMR spectroscopy (400-800 MHz) to study samples in solution and observe active nuclei ( 1H, 13C, 19F, 31P, 113Cd, 195Pt, 29Si, 15N, etc.).Nuclear magnetic resonance (NMR) Techniques

Analyse spectrale rmn